The UGT1A1 coding sequence variant c.211 G > A (UGT1A1*6, G71R), the main cause of Gilbert syndrome in East Asia, was also the predominant association factor with high TSB levels and neonatal hyperbilirubinemia risk in the Asian population without any additional icterogenic factors [14, 15, 22–25]. This evidence concerns the gene UGT1A1 and Hyperbilirubinemia.