Concomitant with the EMT process induced by TGF-β in the HCC cells, here we observe an increased expression of fatty acid transporters, including various members of the family of fatty acid-binding proteins (FABPs) and the family of long-chain fatty acid transporters, solute carrier family 27 (SLC27), suggesting an increased fatty acid uptake that correlates with the higher level of intracellular FFA. Here, TGFB1 is linked to hepatocellular carcinoma.