The advantages of this vaccine over the SVs described above is that it mimics a natural infection without causing serious influenza illness and induces antibodies of both IgA, which is an important isotype for mucosal immunity to provide initial protection against influenza viruses at the entry site, and IgG, which is the most important class of antibody for neutralization of influenza viruses in the tissues and blood stream [44]. Here, CD79A is linked to infection.