NFKB1 and Alzheimer disease: In aluminum chloride (AlCl3) and D-galactose (D-Gal) induced AD rats, treatments of TQ (10, 20, and 40 mg/kg/day for 14 days) ameliorated cognitive decline in AD rats by decreasing Aβ formation and accumulation and by inhibiting inflammatory response through the downregulation of NF-κB pathway [54].