PLAT and obesity due to melanocortin 4 receptor deficiency: There was no significant difference (p > 0.1) between the patients who received MT or solely tPA with regard to the average age (respectively; 69 ± 12.2 vs. 71 ± 12.6 years), the distribution of sex (52.4% vs. 50.6% females), the frequency of the main vascular risk factors (hypertension 75% vs. 73%, diabetes 25% vs. 21%, AF 42% vs. 35%, CHD 25% vs. 24%, dyslipidemia 32% vs. 28%, smoking 26% vs. 21%, obesity 21% vs. 30%, past stroke 13% vs. 14%) and the frequency of large artery atherosclerotic and cardioembolic strokes (respectively, 51% and 42% vs. 46% and 35%).