A similar correlation was also found between maternal protein restriction and histone modifications on the glucose transporter type 4 (GLUT4) gene resulting in the overexpression of GLUT4 in the skeletal muscle of the female offspring [133], as well as histone modifications on the GATA binding protein 6 (GATA6) gene, which is associated with cardiovascular and metabolic diseases in adulthood [134]. This evidence concerns the gene GATA6 and Other metabolic disease.