CD40LG and Hypertension: Further, Su J. et al. suggested that individuals with high levels of IgM isotypes against phosphorylcholine (PC) (OR: 0.46), Ox-LDL (OR: 0.46), and MDA-modified LDL (OR: 0.27) can predict a decreased rate of development of carotid intima medium thickness (IMT) in patients with hypertension [43].