Plasma levels of IgM against the IGKC76–99 unmodified peptide between patients with CAD with >70% stenosis were significantly 0.52-fold (p = 0.0009) lower than those of HCs, and patients with CAD with 30~70% stenosis were 0.58-fold (p = 0.0122) lower than those of HCs (Supplementary Figure S2H, left panel). The gene discussed is CD40LG; the disease is coronary artery disorder.