CD40LG and rheumatoid arthritis: Moreover, in the previous study carried out by Liao C.C. et al. suggested that IgG and IgM isotypes against four different novel MDA-modified peptides (Ig kappa chain C region (IGKC76–99), alpha-1-antitrypsin (A1AT284–298), alpha-2-macroglobulin (A2M824–841), and apolipoprotein B-100 (ApoB1004022–4040) can differentiate patients with RA and healthy controls (HCs) with an AUC of 0.96–0.98 [25].