In G93A-SOD1 mice, this increment was already significant at week 8 (presymptomatic disease phase) and was maintained until week 18 (symptomatic phase) as previously observed [52,67,68], suggesting a protective role for miR-206 by inducing muscle regeneration during ALS progression to counteract muscle wasting. This evidence concerns the gene SOD1 and amyotrophic lateral sclerosis.