We assessed the expression levels of miR-206, miR-133a, miR-133b and miR-1 in serum of mutant-SOD1-ALS, pediatric SMA, and SBMA patients (as illustrated in Table 1), to evaluate the potential of these myomiRs as noninvasive clinical biomarkers in the human pathologies. The gene discussed is SOD1; the disease is amyotrophic lateral sclerosis.