To try to understand the mechanistic relationship between the NTNG1 locus and cerebral atherosclerosis, we tested the two independent significant SNPs for proximal and distal eQTL and pQTL effects on brain RNA and protein levels of NTNG1 and 237 other genes that showed differential protein expression in cerebral atherosclerosis in a previous proteomic analysis in human brain [12]. Here, NTNG1 is linked to cerebral atherosclerosis.