The prognostic value of Gal-3 for long-term events among patients with HF and preserved ejection fraction were confirmed by French et al. They compared the prognostic accuracy of galectin-3, soluble ST2 (sST2) (a member of the superfamily of interleukin (IL)-1 receptors), troponin I and BNP at 1 and 5 years in 1385 patients with reduced, preserved and recovered LVEF. Here, LGALS3 is linked to hydrops fetalis.