The Top 5 over-expressed BAE proteins during infection are Nitric oxide synthase (NOS3, Fcaverage = 4.2), Cell surface glycoprotein MCAM (Fcaverage = 3.5), Integrin alpha-5 (ITGA5, Fcaverage = 3.2), Tubulointerstitial nephritis antigen-like 1 (TINAGL1, Fc average = 3.2) and Leucine-rich PPR motif-containing protein (LRPPRC, Fcaverage 3.1) (Supplementary Table S2). The gene discussed is ITGA5; the disease is infection.