Moon et al. [51] were involved for the first time with fibronectin (FN) present on the EV surface detected in plasma samples from disease-free individuals (n = 70), patients with BC (n = 240), patients with BC after surgical resection (n = 40), patients with benign breast tumor (n = 55), and patients with non-cancerous diseases (thyroiditis, gastritis, hepatitis B, and rheumatoid arthritis; n = 80). The gene discussed is FN1; the disease is rheumatoid arthritis.