Our results also show that even though there is an increasing trend in the expression of several ERRα target genes involved in the glycolytic pathway, such as lactate dehydrogenase B (LDHB) and hexokinase-2 (HK2), no significant alteration was seen in their gene expression levels in the basal-like breast tumours of overweight/obese patients compared to the lean patients (Figure 7D). Here, HK2 is linked to breast neoplasm.