Furthermore, examination of a TCGA lung adenocarcinoma cohort validated that PD-L1 (CD274) was positively correlated with YAP (YAP1), TAZ (WWTR1), and the YAP/TAZ signature (Figure 3H), and NSCLC patients with high PD-L1 expression conferred poor survival probabilities (Figure 3I). This evidence concerns the gene WWTR1 and lung adenocarcinoma.