HIF1A and pancreatic adenocarcinoma: To confirm the expression of HIF-1α in tumors, we searched and analyzed the data in the GEPIA database and found that HIF-1α was more highly expressed in liver hepatocellular carcinoma (LIHC) (Figure 1A), glioblastoma multiforme (GBM) (Figure 1B), pancreatic adenocarcinoma (PAAD) (Figure 1C) and acute myeloid leukemia (LAML) (Figure 1D) tissues than in healthy tissues.