To determine whether an Akt antagonist and panobinostat have similar functions or whether an Akt agonist can block functions of panobinostat, we examined the protein expression levels of p-Akt, FOXM1, and MMP-9 using the Akt inhibitor LY2940002 and the Akt agonist SC97 in GC cells. This evidence concerns the gene FOXM1 and gastric cancer.