NFKB1 and malignant colon neoplasm: It has been proven by studies that cancer metastasis-related to epithelial-mesenchymal transition (EMT) is one of the most important causes of death of colon cancer and several signaling pathways such as RTK/Ras, Notch, NF-κB, and Wnt/β-catenin are associated with the activation of EMT.