NOS2 and irritable bowel syndrome: In an in vivo murine model of IBD induced by the intracolonic administration of dinitrobenzene sulphonic acid (DNBS), cannabigerol (CBG) reduced the expression of inducible nitric oxide synthase (iNOS), as well as the levels of IL-1β, IL-10 and IFN-γ, and the activity of myeloperoxidase, while increasing the activity of superoxide dismutase [70].