In 115 healthy, overweight/moderately obese adults with BMI ranging from 25 to 36.9 kg/m2, McLaughlin et al. found that despite nearly identical mean BMI values in the insulin-resistant and insulin-sensitive groups, visceral adipose tissue, quantified by CT results, was significantly higher in the insulin resistance group, whereas subcutaneous adipose tissue was significantly lower [102]. This evidence concerns the gene INS and Insulin resistance.