LncRNAs are involved in the regulation of oncogene expression, which induces metabolic reprogramming of HIF 1 α, c-MYC or p53 [195,196], but they can also interact with tumor suppressors, such as AMPK [197], oncogenic signaling pathways, metabolic enzymes or with other ncRNAs [193,194]. This evidence concerns the gene MYC and neoplasm.