In line with this, high frequency of PDL1/PDL2-involving genetic aberrations was observed in EBV-associated lymphomas, including extranodal NK/T-cell lymphoma, aggressive NK-cell leukemia, systemic EBV-positive T-cell lymphoproliferative disorder, peripheral T-cell lymphoma, not otherwise specified, and EBV + DLBCL [76,80]. Here, CD274 is linked to diffuse large B-cell lymphoma.