BRCA1 and cancer: It is interesting that the high rate of above 50% in LPV/PV detected in patients diagnosed with both cancers (breast and ovary, synchronic, or metachronic) is kept in those numbers since our results published in 2012 [35] with only 134 patients, maintained with 940 probands [36] and consolidated in this work with 2155 patients in which the patients with both cancers showed a detection rate of a PV in BRCA1/2 of 51.8%