Additional studies have identified BRCA1/2 pathogenic variants in up to 29% of patients of Ashkenazi Jewish ethnicity presenting with TNBC [20], 20% of those with TNBC diagnosed at a young age and/or with a family history of breast cancer, and 8–14% of those with TNBC unselected for family history [21,22]. This evidence concerns the gene BRCA1 and breast cancer.