To find possible determinants of deterioration of kidney function, we performed Fine and Gray regression analysis on an exploratory basis for all variables in Table 1, and we found that only baseline eGFR (SHR 0.97, 95%CI 0.95–0.99, p = 0.032), SBP (SHR 0.96, 95%CI 0.93–0.99, p = 0.01), T2DM duration (SHR 1.06, 95%CI 1.00–1.11, p = 0.03) and serum albumin (SHR 0.25, 95%CI 0.11–0.60, p = 0.002) were associated with the composite outcome. The gene discussed is ALB; the disease is type 2 diabetes mellitus.