TREX1 and Autoimmunity: Since (a) B and T cells are more sensitive to irradiation [28,29,111]; (b) TREX1 activity is decreased in various autoimmune conditions [37,38,39,40]; and (c) B and T cells’ immunogenicity is a key contributor to the autoimmunity, researchers could tackle the question whether low-dose irradiation could be exploited to ameliorate autoimmunity.