In addition, as shown in representative cases, the percentage of CD4+CD25+FOXP3+ T cells that were CD45RO+ was lower in the 1-year-old control and the 1-year-old allergic subject no. 2 that had both food allergy and atopic dermatitis than that in the allergic subject no. 3, an 9.7-year-old child with paediatric allergic asthma (Figure 1b). Here, CD4 is linked to allergic asthma.