However, the role of microglia in stroke is yet not clear, since it contributes to post-ischemic inflammation by producing proinflammatory cytokines such as TNF and IL-1β, while they also contribute to tissue repair by producing IL-10, tissue growth factor- β (TGF- β), and insulin-like growth factor 1 (IGF-1) [24]. This evidence concerns the gene TNF and Stroke.