We also observed that in tumor lysates from the treated mice that the NR4A1-regulated gene products EGFR, cMET, PD-L1, and phosphorylated mTOR were decreased (Figure 7A,B) and that these in vivo results complement the in vitro studies in MDA-MB-231 cells (Figure 3). This evidence concerns the gene NR4A1 and neoplasm.