Treatment with 5–10 μM 3-Br-5-OCH3, 3-Cl-5-OCF3, 3-Cl-5-CF3, and 3-Br-5-OCF3 (Figure 4A–D, respectively) inhibited the growth of SKBR3 breast cancer cells and, treatment-related growth and inhibition were significantly attenuated after the NR4A1 knockdown by RNAi (Figure 4E illustrates the effectiveness of RNAi in decreasing NR4A1 protein). This evidence concerns the gene NR4A1 and breast cancer.