In the context of miRNA-based therapy, miR-135a-loaded cationic immunoliposomes coated with anti-EGFR (Epidermal Growth Factor Receptor) antibodies (Anti-EGFR-CIL-miR-135a) were shown to inhibit gallbladder carcinoma invasion (GBC) and metastasis, and to promote apoptosis. The gene discussed is EGFR; the disease is gallbladder carcinoma.