In RMT Bl6 the level of Egf (p = 0.0006) was reduced, whereas the expressions of Nrg1 (p ≤ 0.0001) and neuregulin 3 (Nrg3, p ≤ 0.0001) were increased compared to HCC group (Figure 11A,B,D). The gene discussed is NRG3; the disease is hepatocellular carcinoma.