In HCC mice, there was a significant elevation of Grin1 (p = 0.05), Grin2b (p = 0.009) and dopamine receptor D1 (Drd1, p = 0.009) in 129Sv compared to Bl6 strain (Figure 7A,B,D). The gene discussed is DRD1; the disease is hepatocellular carcinoma.