HBEGF and hepatocellular carcinoma: RMT induced an elevation of Egf (p = 0.007), Tgfa (p ≤ 0.0001), heparin binding EGF like growth factor (Hb-Egf, p = 0.0003), neuregulin 2 (Nrg2, p ≤ 0.0001) and erb-b2 receptor tyrosine kinase 3 (Erbb3, p = 0.005) in 129Sv compared to HCC group (Figure 10A,B,D).