BOC and colitis: In post-colitis animals, a single administration of the serine protease inhibitor significantly decreased trypsin-like activity compared to vehicle-treated animals (Boc-Gln-Ala-Arg-AMC: 0.24 (0.87) U/g versus 0.87 (0.67) U/g, p < 0.01, Tos-Gly-Pro-Arg-AMC: 0.23 (0.18) U/g versus 1.08 (1.19) U/g, p < 0.01, n = 12 per group, Figure 6A,B).