LINGO1 and essential thrombocythemia: The first two GWAS reported, respectively, an association of the risk for ET with two SNPs in the Leucine rich repeat and Ig domain containing Nogo receptor interacting protein-1 gene (LINGO1) [59,60], and with an intronic variant in the solute carrier family 1-glial affinity glutamate transporter-, member 2 (SLC1A2) gene with ET [60].