The second GWAS described a strong association (odds ratio (95% CI) = 1.59 (1.36–1.84)) between the SNP rs3794087 in the SLC1A2 gene and the risk for definite ET in a GWAS of 990 patients with ET (658 with definite ET) and 1490 healthy controls [60]. Here, SLC1A2 is linked to essential thrombocythemia.