Analysis of the promoter nucleotide sequences of genes involved in the pathogenesis of AD (CASP3, TP53, SOD2, GPX1, PPARA, PPARG, NES, GAP43, SUMO1, APOE and IGF1) showed the presence of DNA sequences found in low-energy complexes using molecular docking of the EDR peptide. Here, APOE is linked to Alzheimer disease.