The most commonly used scoring systems are Maddrey’s discriminant function (MDF), the model for end-stage liver disease (MELD) score, the age, serum bilirubin, international normalized ratio, creatinine (ABIC) score, the Glasgow alcoholic hepatitis (GAHS) score, and the LILLE score (age, renal insufficiency, albumin, prothrombin time, bilirubin baseline and at 7 days) [6]. The gene discussed is ALB; the disease is Renal insufficiency.