SH2D3C and infection: A study in 2018 showed that the interactions between two conserved motifs in CHIKV nsP3 HVD—the proline-rich (P-rich) region and the FGDF-like duplicate motifs—and Aedes aegypti cellular proteins are important in the infection and dissemination of CHIKV in the Ae. aegypti mosquito vector [96].