AGT and diabetic kidney disease: In T2DM study subjects from the Health Professionals Follow-Up Study (HPFS) and the Nurses’ Health Study (NHS), sex-specific associations were found between the angiotensin II type 1 receptor gene AGT1R 1166 C-allele and AGT 235T and coronary heart disease (CHD), whereas the AGT1R T573 C-allele variant was not associated with CHD or DKD [191].