Furthermore, some authors have demonstrated that the hypermethylation of Septine 9 (guanosine triphosphatase class gene) is related to CRC development [101,102] and is found in 58–96% of CRC patients, and in only 18% of CA subjects with specificities of 86–100% [101,102,103,104]. Here, SEPTIN9 is linked to colorectal carcinoma.