Some clinical investigations have demonstrated the role of other chemokines, such as CCL20 (CC-chemokine ligand 20) and its specific receptor CCR6 (CC-chemokine receptor 6), receptor CXCR3 (CXC chemokine receptor 3) as well as CXCL5 (CXC motif chemokine 5), in CRC pathogenesis [51,52,53,54,55]. The gene discussed is CCR6; the disease is colorectal carcinoma.