MAP2K7 and non-small cell lung carcinoma: YAP/TAZ have been shown to play a role in establishing the DTP state in EGFR-mutant NSCLC cells treated with combination EGFR and MEK inhibitors by transcriptional reprogramming of apoptotic pathways [56]; however, whether BRD4 or other BET proteins play a role in this process remains to be elucidated.