[Gd@C82(OH)22]n induce dendritic cells (DCs) to become functionally mature and activate allogeneic T cells in tumor-bearing mice to eradicate foreign pathogens and scavenge tumors and depress the viability of the tumor by activating TNF-α mediated cellular immunity (Figure 2) [6,36,46,49,50]. This evidence concerns the gene TNF and neoplasm.