While the role of NF-κB in cancer by regulating immunity and inflammation is well documented, there are some reports that link NF-κB with tumor progression by regulating apoptosis [139], a function of NF-κB that may be mediated in part by lncRNA PDIA3P1 (protein disulfide isomerase family A member 3 pseudogene 1). The gene discussed is NFKB1; the disease is cancer.