CD4 and COVID-19: In parallel, significantly lower levels of naïve Th (CD3+CD4+CD45RA+) (Figure S3L) and naïve Ts (CD3+CD8+CD45RA+) cells (Figure S3M) were observed from admission to day 7 in the ICU COVID-19 patients (p = 0.043 and p < 0.001, respectively, for naïve Th, and p < 0.001 and p = 0.006, respectively, for naïve Ts cells).