Analyses of 1915 cases of advanced ovarian cancer registered in two clinical trials (GOG 218 and GOG 262) indicated the presence of 14 homologous recombination-related genes (BRIP1, PALB2, RAD51C, RAD51D, ATM, ATR, NBN, SLX4, BARD1, BLM, CHEK2, RBBP8, MRE11A, and XRCC2), in addition to BRCA1/2. This evidence concerns the gene BRCA1 and ovarian cancer.