TPO and autoimmune polyendocrinopathy: At least one of two autoantibodies (TG or TPO) was detected in 10.7% of healthy patients (n = 28), 16.7% of APS-1 patients without AITDs (n = 12), 27.7% of APS-2 patients with a diagnosis of AITD (n = 36), and 31.8% of patients with isolated AITD (n = 22) (Figure 5b).