AFAP1 and laryngeal carcinoma: In laryngeal carcinoma cells, AFAP1-AS1 can upregulate recombination signal binding protein for immunoglobulin kappa J region (RBPJ) expression by negative regulation of hsa-miR-320a-3p, and enforced expression of RBPJ could reduce the stemness and chemoresistance inhibited by AFAP1-AS1 silencing [73].