Platelet factor 4 (PF4)/CXCL4, neutrophil activating peptide 2 (NAP2)/CXCL7, cluster of differentiation 40 ligand (CD40L), and regulated on activation normal T cell expressed and secreted (RANTES)/CCL5 were all found to be elevated in patients with FH, even in cases of intensive lipid-lowering treatment. This evidence concerns the gene PPBP and familial hyperaldosteronism.