However, the G401 and BT16 cell lines, derived from malignant rhabdoid tumors of kidney and atypical teratoid rhabdoid tumor of the MYC-subtype [22], respectively, and thus inherently lacking SMARCB1 were determined to represent the disease state well, and would provide the most relevant data for investigating MRTK and ATRT-MYC. The gene discussed is SMARCB1; the disease is rhabdoid tumor.