CXCL12 and neoplasm: On the other hand, since MDSCs and Tregs are both known to protect tumors from CTL-mediated elimination, and to promote tumor growth, we also analyzed the expression of chemokines attracting MDSCs and Tregs to tumors, that is, CXCL12 and CCL22. As expected, we observed that high-thermogenesis TNBC had a higher expression of CXCL12 (p < 0.01), while no difference in CCL22 expression was observed.