Since we observed lower IFN-γ signature and granzyme B expression with lower CTL-attracting chemokines in the high-thermogenesis TNBC, we hypothesized that anti-cancer immune cell infiltration is lower in high-thermogenesis TNBC, and tested this hypothesis in METABRIC and GSE96058 cohorts using the xCell algorithm. The gene discussed is GZMB; the disease is cancer.