In an open-label, randomized phase III trial at 7 hospitals in China, 202 patients with an FLT3-ITD acute myeloid leukemia, who underwent an aHSCT, were randomly assigned (1:1) to Sorafenib maintenance (400 mg orally twice daily) or non-maintenance (control) at 30–60 days post transplantation. This evidence concerns the gene FLT3 and acute myeloid leukemia.