Miettinen and Sarlomo-Rikala [84] investigated the expression of four so-called mesothelial markers in 596 lung carcinomas of different histology types, demonstrating calretinin expression in 67% of giant cell carcinomas, 49% of small cell carcinomas, 38% of large cell carcinomas, but rarely in adenocarcinomas. The gene discussed is CALB2; the disease is adenocarcinoma.