The absence of these gene rearrangements in our larger sample of CH-TD Mexican patients agree with the data obtained from Japanese (PAX8, NKX2-1, and FOXE1) [16] and Russian (1/243 CH patients with PAX8 heterozygous deletion, no deletions in TPO, FOXE1, NKX2-1, or TSHR) [7] CH patients. Here, NKX2-1 is linked to cyclic hematopoiesis.