FRB supplementation also maintained the mRNA level of Il-10, an anti-inflammatory cytokine (p < 0.001), as shown in Figure 4B. While Il-6 is thought to be involved as a pro-inflammatory cytokine in the pathogenesis of IBD, this cytokine has also been reported to play a role in intestinal mucosal healing [41]. The gene discussed is IL6; the disease is inflammatory bowel disease.