Various animal models have been introduced to mimic the symptoms of IBD, including chemically induced animal models using dextran sodium sulfate (DSS) [6,7,8,9] or 2,4,6-trinitrobenzene sulfonic acid [10], bacteria-induced models such as Salmonella-induced colitis [11], and genetically modified animals such as Il-10 [12] or T cell receptor α [13] knock-out mice. The gene discussed is IL10; the disease is inflammatory bowel disease.